The effect of herbal drugs on neonatal jaundice

Using herbal drugs is the common way for treatment of diseases in traditional and alternative medicine. These drugs have important role and strong cultural background among people in treatment of hyper-billirubinemia. It is necessary to evaluate the effect of herbal drugs by scientific methods. The goal of this study is evaluation the effect of common herbal drugs used in management of neonatal hyper-billirubinemia with in vitro method. Material & methods: In this study 0/5 cc of 5 common herbal drug (Cichorium intybus, Fumaria parvi flora, Zizyphus jujuba, Alhagi psudoalhagi and Purgative manna) which are obtained by Hydrochloric instillation, then the level of billirubin was checked by Diazo blank method. Using herbal drugs is the common way for treatment of diseases in traditional and alternative medicine. These drugs have important role and strong cultural background among people in treatment of hyper-billirubinemia. It is necessary to evaluate the effect of herbal drugs by scientific methods. The goal of this study is evaluation the effect of common herbal drugs used in management of neonatal hyper-billirubinemia with in vitro method. The other herbal drugs may be decrease billirubin level with another mechanism, for example by cathartic effect or activation of liver enzymes, but this study revealed the only drug with direct decreasing effect on billirubin is Cichorium intybus. Therefore the effective substance of Cichorium intybus must be separated and will used in in vivo method.